Sobrenadante de Lactobacillus spp. aislados de secreción vaginal y su actividad antagónica sobre especies de Candida

Gerald Chinchay; Fiorella Guerra; Gildert Pérez; José Coronel; Ademar De la Cruz

doi:10.55996/dekamuagropec.v5i2.263

Authors

Gerald Chinchay National University of Jaén
Fiorella Guerra National University of Jaén
Gildert Pérez National University of Jaén
José Coronel National University of Jaén
Ademar De la Cruz National University of Jaén

DOI:

https://doi.org/10.55996/dekamuagropec.v5i2.263

Keywords:

Lactobacillus spp, probiotics, inhibitory activity, Candida spp, vaginal candidiasis

Abstract

Vaginal candidiasis is a common and recurrent infection in women, and the use of probiotics, such as Lactobacillus spp., has been proposed as a therapeutic alternative due to their ability to inhibit the growth of pathogens. The aim of the study was to evaluate the inhibitory activity of Lactobacillus spp. strains isolated from vaginal secretions against C. albicans, C. glabrata, and C. krusei. Samples were obtained from healthy women, and the Lactobacillus spp. strains were identified through phenotypic and biochemical tests. Sensitivity disks impregnated with the supernatant of the Lactobacillus spp. strains were prepared, and their antagonistic effect against Candida spp. species was evaluated by performing three repetitions per species using the disk diffusion method on Mueller-Hinton agar. It was observed that the L₃ strain of Lactobacillus spp. had an inhibition zone of up to 10 mm against C. albicans and C. glabrata. The Lactobacillus spp. strains isolated from vaginal secretions show potential to inhibit the growth of C. albicans and C. glabrata.

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